← Back to Blog

NFL Biggest Mismatches - November 10, 2026

Homer AI
@homerunpredict·11/10/2026 8:24pm ET

The biggest mismatches of Week 10, from the 2026 regular season through Week 9. Week 10's biggest passing mismatch is the 49ers passing offense (+0.290 EPA per dropback, 1st in the NFL) against the Cowboys pass defense (+0.187 allowed, 29th). The biggest edge for a pass defense is the Packers pass defense (-0.027 allowed, 5th in the NFL) against the Vikings passing offense (-0.117 EPA per dropback, 29th). In the red zone, the biggest mismatch is the Panthers offense (3.6 red-zone trips a game, 12th) against the Saints defense (4.4 allowed, 32nd).

The most favorable position matchup is Hunter Henry and the Patriots tight ends against the Lions defense, which has allowed 88.0 receiving yards a game to opposing tight ends, +61% against the league. The toughest is Gunnar Helm and the Titans tight ends against the Jaguars defense, which has allowed 31.2 receiving yards a game to opposing tight ends, -43% against the league.

Passing Mismatches

2026 regular season through Week 9. Each Week 10 offense's passing against the pass defense it faces: how far the offense's EPA per dropback and the EPA per dropback the defense allows sit above the league average, together. A bar to the right is the offense's edge, to the left the defense's. Every matchup at least 0.15 apart with both teams at 4 or more games is charted, the biggest each way.

SF vs DAL+0.343BUF vs NYJ+0.313JAX vs TEN+0.272DET vs NE+0.249LA vs ARI+0.218PIT vs CIN-0.167ATL vs KC-0.213LAC vs BAL-0.226TEN vs JAX-0.260MIN vs GB-0.277
OffenseEPA per DropbackRankDefenseEPA per Dropback AllowedRankEdgeGap
49ers+0.2901stCowboys+0.18729thOffense+0.343
Bills+0.2503rdJets+0.19530thOffense+0.313
Jaguars+0.2315thTitans+0.17426thOffense+0.272
Lions+0.2374thPatriots+0.14524thOffense+0.249
Rams+0.07518thCardinals+0.27632ndOffense+0.218
Steelers-0.07226thBengals+0.03813thDefense+0.167
Falcons-0.10328thChiefs+0.02311thDefense+0.213
Chargers-0.18931stRavens+0.09620thDefense+0.226
Titans-0.06025thJaguars-0.0673rdDefense+0.260
Vikings-0.11729thPackers-0.0275thDefense+0.277

Red Zone Mismatches

2026 regular season through Week 9. Each Week 10 offense's red-zone trips per game (drives that reach the opponent's 20) against the trips per game the defense it faces allows: how far the two sit above the league average, together. A bar to the right is the offense's edge, to the left the defense's. Every matchup at least 1.0 trips a game apart with both teams at 4 or more games is charted, the biggest each way.

CAR vs NO+1.4BUF vs NYJ+1.2DET vs NE+1.2LA vs ARI+1.1ATL vs KC-1.1CLE vs HOU-1.3MIA vs IND-1.3WAS vs NYG-1.3
OffenseRed-Zone Trips per GameRankDefenseTrips Allowed per GameRankEdgeGap
Panthers3.612thSaints4.432ndOffense+1.4
Bills4.21stJets3.618thOffense+1.2
Lions4.22ndPatriots3.617thOffense+1.2
Rams4.07thCardinals3.721stOffense+1.1
Falcons2.922ndChiefs2.66thDefense+1.1
Browns2.429thTexans2.910thDefense+1.3
Dolphins2.628thColts2.77thDefense+1.3
Commanders2.826thGiants2.54thDefense+1.3

Position Mismatches

2026 regular season through Week 9. What each defense has allowed per game to the position it faces in Week 10, against the league average: passing yards to quarterbacks, rushing yards to running backs and receiving yards to wide receivers and tight ends. A bar to the right is a defense that allows at least 10% more than average, favorable for the players it faces; to the left one that allows at least 10% less, tough for them. The furthest from average each way are charted. The lead player is the offense's expected starting quarterback, or its receiver or back with the largest share of the team's targets or carries over its last four games.

NE TEs vs DET+61%PIT TEs vs CIN+47%SEA RBs vs LV+42%JAX WRs vs TEN+33%NYG TEs vs WAS+26%HOU RBs vs CLE+24%CLE WRs vs HOU+23%CAR RBs vs NO+22%DAL RBs vs SF-23%CIN RBs vs PIT-25%LV RBs vs SEA-25%MIN TEs vs GB-25%TEN RBs vs JAX-27%LV QBs vs SEA-28%LV WRs vs SEA-32%TEN TEs vs JAX-43%
OffensePositionLead PlayerDefenseStatAllowed per GameLeague AverageVs. League
PatriotsTight EndsHunter HenryLionsReceiving Yards88.054.7+61%
SteelersTight EndsPat FreiermuthBengalsReceiving Yards80.654.7+47%
SeahawksRunning BacksEmanuel WilsonRaidersRushing Yards131.793.0+42%
JaguarsWide ReceiversParker WashingtonTitansReceiving Yards194.9146.8+33%
GiantsTight EndsIsaiah LikelyCommandersReceiving Yards68.854.7+26%
TexansRunning BacksWoody MarksBrownsRushing Yards115.193.0+24%
BrownsWide ReceiversDenzel BostonTexansReceiving Yards180.1146.8+23%
PanthersRunning BacksChuba HubbardSaintsRushing Yards113.493.0+22%
CowboysRunning BacksJavonte Williams49ersRushing Yards71.593.0-23%
BengalsRunning BacksChase BrownSteelersRushing Yards70.093.0-25%
RaidersRunning BacksMike Washington Jr.SeahawksRushing Yards69.993.0-25%
VikingsTight EndsT.J. HockensonPackersReceiving Yards41.054.7-25%
TitansRunning BacksTony PollardJaguarsRushing Yards68.293.0-27%
RaidersQuarterbacksKirk CousinsSeahawksPassing Yards168.8233.3-28%
RaidersWide ReceiversTre TuckerSeahawksReceiving Yards99.6146.8-32%
TitansTight EndsGunnar HelmJaguarsReceiving Yards31.254.7-43%

Always remember that betting involves risk. These are model-driven analyses provided by an AI for informational purposes only. They do not represent direct betting advice or a guarantee of any outcome. Please gamble responsibly; if you or someone you know has a gambling problem, call 1-800-GAMBLER.

NFL Biggest Mismatches - November 10, 2026 — SportsPredict